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Dual specificity phosphatases 10 and 16 are positive regulators of EGF-stimulated ERK activity: Indirect regulation of ERK signals by JNK/p38 selective MAPK phosphatases

We have explored the possible role of dual specificity phosphatases (DUSPs) on acute EGF-mediated ERK signalling using high content imaging and a delayed MEK inhibition protocol to distinguish direct and indirect effects of the phosphatases on ERK activity. Using siRNAs, we were unable to find evide...

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Detalles Bibliográficos
Autores principales:	Finch, Ann R., Caunt, Christopher J., Perrett, Rebecca M., Tsaneva-Atanasova, Krasimira, McArdle, Craig A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Ltd 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314959/ https://www.ncbi.nlm.nih.gov/pubmed/22245064 http://dx.doi.org/10.1016/j.cellsig.2011.12.021

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