Cargando…

FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling

Lipolysis is defined as the catabolism of triacylglycerols stored in cellular lipid droplets. Recent discoveries of essential lipolytic enzymes and characterization of numerous regulatory proteins and mechanisms have fundamentally changed our perception of lipolysis and its impact on cellular metabo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zechner, Rudolf, Zimmermann, Robert, Eichmann, Thomas O., Kohlwein, Sepp D., Haemmerle, Guenter, Lass, Achim, Madeo, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314979/ https://www.ncbi.nlm.nih.gov/pubmed/22405066 http://dx.doi.org/10.1016/j.cmet.2011.12.018

Ejemplares similares

The Role of Adipose Triglyceride Lipase and Cytosolic Lipolysis in Cardiac Function and Heart Failure
por: Kintscher, Ulrich, et al.
Publicado: (2020)

Fat in the skin: Triacylglycerol metabolism in keratinocytes and its role in the development of neutral lipid storage disease
por: Radner, Franz PW, et al.
Publicado: (2011)

Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores
por: Lass, Achim, et al.
Publicado: (2011)

Remodeling of Lipid Droplets during Lipolysis and Growth in Adipocytes
por: Paar, Margret, et al.
Publicado: (2012)

Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism
por: Heier, Christoph, et al.
Publicado: (2016)

Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling
por: Hofer, Peter, et al.
Publicado: (2015)

Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A
por: Nagy, Harald M., et al.
Publicado: (2014)

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover
por: Grumet, Lukas, et al.
Publicado: (2016)

Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells
por: Taschler, Ulrike, et al.
Publicado: (2015)

FAT FLUX: enzymes, regulators, and pathophysiology of intracellular lipolysis
por: Zechner, Rudolf
Publicado: (2015)

DAG tales: the multiple faces of diacylglycerol—stereochemistry, metabolism, and signaling
por: Eichmann, Thomas Oliver, et al.
Publicado: (2015)

ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6
por: Eichmann, Thomas O., et al.
Publicado: (2015)

Development of small molecule inhibitors targeting adipose triglyceride lipase
por: Mayer, Nicole, et al.
Publicado: (2013)

Role of the ubiquitin–proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice
por: Mussbacher, Marion, et al.
Publicado: (2014)

Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE−/− mice
por: Vujic, Nemanja, et al.
Publicado: (2017)

Yeast and cancer cells – common principles in lipid metabolism
por: Natter, Klaus, et al.
Publicado: (2013)

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase
por: Chandak, Prakash G., et al.
Publicado: (2010)

Micro RNA-124a Regulates Lipolysis via Adipose Triglyceride Lipase and Comparative Gene Identification 58
por: Das, Suman K., et al.
Publicado: (2015)

Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice
por: Vujic, Nemanja, et al.
Publicado: (2015)

Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue
por: Schreiber, Renate, et al.
Publicado: (2017)

ABHD5 stimulates PNPLA1-mediated ω-O-acylceramide biosynthesis essential for a functional skin permeability barrier
por: Kien, Benedikt, et al.
Publicado: (2018)

Endothelial dysfunction in adipose triglyceride lipase deficiency
por: Schrammel, Astrid, et al.
Publicado: (2014)

Enhanced monoacylglycerol lipolysis by ABHD6 promotes NSCLC pathogenesis
por: Tang, Zhiyuan, et al.
Publicado: (2020)

Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes
por: Grabner, Gernot F., et al.
Publicado: (2022)

Lipolysis: more than just a lipase
por: Birnbaum, Morris J.
Publicado: (2003)

Adverse cardiac remodeling augments adipose tissue ß-adrenergic signaling and lipolysis counteracting diet-induced obesity
por: Kolleritsch, Stephanie, et al.
Publicado: (2023)

Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomycescerevisiae
por: Heier, Christoph, et al.
Publicado: (2010)

Lipid Droplets and Peroxisomes: Key Players in Cellular Lipid Homeostasis or A Matter of Fat—Store ’em Up or Burn ’em Down
por: Kohlwein, Sepp D., et al.
Publicado: (2013)

Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice
por: Schweiger, Martina, et al.
Publicado: (2017)

A versatile ultra-high performance LC-MS method for lipid profiling()
por: Knittelfelder, Oskar L., et al.
Publicado: (2014)

Pigment Epithelium–Derived Factor Regulates Lipid Metabolism via Adipose Triglyceride Lipase
por: Borg, Melissa L., et al.
Publicado: (2011)

Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis
por: Schlager, Stefanie, et al.
Publicado: (2015)

Nitric oxide signaling in adipose triglyceride lipase-deficient microvascular endothelial cells
por: Mussbacher, Marion, et al.
Publicado: (2012)

A Peptide Derived from G(0)/G(1) Switch Gene 2 Acts as Noncompetitive Inhibitor of Adipose Triglyceride Lipase
por: Cerk, Ines K., et al.
Publicado: (2014)

Plasma Lipolysis and Changes in Plasma and Cerebrospinal Fluid Signaling Lipids Reveal Abnormal Lipid Metabolism in Chronic Migraine
por: Castor, Katherine, et al.
Publicado: (2021)

Corrigendum: Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice
por: Schweiger, Martina, et al.
Publicado: (2017)

Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase
por: Pajed, Laura, et al.
Publicado: (2021)

Adipose triglyceride lipase–mediated lipid catabolism is essential for bronchiolar regeneration
por: Kanti, Manu Manjunath, et al.
Publicado: (2022)

Myocardial Adipose Triglyceride Lipase Overexpression Protects Diabetic Mice From the Development of Lipotoxic Cardiomyopathy
por: Pulinilkunnil, Thomas, et al.
Publicado: (2013)

The lipase cofactor CGI58 controls placental lipolysis
por: Guerrero-Santoro, Jennifer, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_rm1racc5098kv244od3ql9tkrp