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Microscale oxygraphy reveals OXPHOS impairment in MRC mutant cells

Given the complexity of the respiratory chain structure, assembly and regulation, the diagnostic workout for the identification of defects of oxidative phosphorylation (OXPHOS) is a major challenge. Spectrophotometric assays, that measure the activity of individual respiratory complexes in tissue an...

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Detalles Bibliográficos
Autores principales: Invernizzi, F., D'Amato, I., Jensen, P.B., Ravaglia, S., Zeviani, M., Tiranti, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314980/
https://www.ncbi.nlm.nih.gov/pubmed/22310368
http://dx.doi.org/10.1016/j.mito.2012.01.001