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Microscale oxygraphy reveals OXPHOS impairment in MRC mutant cells
Given the complexity of the respiratory chain structure, assembly and regulation, the diagnostic workout for the identification of defects of oxidative phosphorylation (OXPHOS) is a major challenge. Spectrophotometric assays, that measure the activity of individual respiratory complexes in tissue an...
Autores principales: | Invernizzi, F., D'Amato, I., Jensen, P.B., Ravaglia, S., Zeviani, M., Tiranti, V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314980/ https://www.ncbi.nlm.nih.gov/pubmed/22310368 http://dx.doi.org/10.1016/j.mito.2012.01.001 |
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