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Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome

BACKGROUND: A sexual dimorphism exists in the incidence and prevalence of coronary artery disease—men are more commonly affected than are age-matched women. We explored the role of the Y chromosome in coronary artery disease in the context of this sexual inequity. METHODS: We genotyped 11 markers of...

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Detalles Bibliográficos
Autores principales: Charchar, Fadi J, Bloomer, Lisa DS, Barnes, Timothy A, Cowley, Mark J, Nelson, Christopher P, Wang, Yanzhong, Denniff, Matthew, Debiec, Radoslaw, Christofidou, Paraskevi, Nankervis, Scott, Dominiczak, Anna F, Bani-Mustafa, Ahmed, Balmforth, Anthony J, Hall, Alistair S, Erdmann, Jeanette, Cambien, Francois, Deloukas, Panos, Hengstenberg, Christian, Packard, Chris, Schunkert, Heribert, Ouwehand, Willem H, Ford, Ian, Goodall, Alison H, Jobling, Mark A, Samani, Nilesh J, Tomaszewski, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lancet Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314981/
https://www.ncbi.nlm.nih.gov/pubmed/22325189
http://dx.doi.org/10.1016/S0140-6736(11)61453-0