The X-Linked Intellectual Disability Protein TSPAN7 Regulates Excitatory Synapse Development and AMPAR Trafficking

Mutations in TSPAN7—a member of the tetraspanin protein superfamily—are implicated in some forms of X-linked intellectual disability. Here we show that TSPAN7 overexpression promotes the formation of filopodia and dendritic spines in cultured hippocampal neurons from embryonic rats, whereas TSPAN7 s...

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Detalles Bibliográficos
Autores principales: Bassani, Silvia, Cingolani, Lorenzo A., Valnegri, Pamela, Folci, Alessandra, Zapata, Jonathan, Gianfelice, Antonella, Sala, Carlo, Goda, Yukiko, Passafaro, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314997/
https://www.ncbi.nlm.nih.gov/pubmed/22445342
http://dx.doi.org/10.1016/j.neuron.2012.01.021

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