Gossypol Inhibits Electron Transport and Stimulates ROS Generation in Yarrowia lipolytica Mitochondria

This work studied the effect of gossypol on the mitochondrial respiratory chain of Yarrowia lipolytica. The compound was shown to inhibit mitochondrial electron transfer and stimulate generation of reactive oxygen species. The inhibition kinetics in oxidation of various substrates (NADH, succinate,...

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Detalles Bibliográficos
Autores principales: Arinbasarova, Anna Yu, Medentsev, Alexander G, Krupyanko, Vladimir I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315064/
https://www.ncbi.nlm.nih.gov/pubmed/22481982
http://dx.doi.org/10.2174/1874091X01206010011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315064/
https://www.ncbi.nlm.nih.gov/pubmed/22481982
http://dx.doi.org/10.2174/1874091X01206010011

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