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A pre-initiation complex at the 3′-end of genes drives antisense transcription independent of divergent sense transcription

The precise nature of antisense transcripts in eukaryotes such as Saccharomyces cerevisiae remains elusive. Here we show that the 3′ regions of genes possess a promoter architecture, including a pre-initiation complex (PIC), which mirrors that at the 5′ region and which is much more pronounced at ge...

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Detalles Bibliográficos
Autores principales: Murray, Struan C., Serra Barros, Ana, Brown, David A., Dudek, Peter, Ayling, Jonathan, Mellor, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315312/
https://www.ncbi.nlm.nih.gov/pubmed/22123739
http://dx.doi.org/10.1093/nar/gkr1121

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