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A pre-initiation complex at the 3′-end of genes drives antisense transcription independent of divergent sense transcription
The precise nature of antisense transcripts in eukaryotes such as Saccharomyces cerevisiae remains elusive. Here we show that the 3′ regions of genes possess a promoter architecture, including a pre-initiation complex (PIC), which mirrors that at the 5′ region and which is much more pronounced at ge...
Autores principales: | Murray, Struan C., Serra Barros, Ana, Brown, David A., Dudek, Peter, Ayling, Jonathan, Mellor, Jane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315312/ https://www.ncbi.nlm.nih.gov/pubmed/22123739 http://dx.doi.org/10.1093/nar/gkr1121 |
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