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Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells

In eukaryotes, the three families of ATP-dependent DNA ligases are associated with specific functions in DNA metabolism. DNA ligase I (LigI) catalyzes Okazaki-fragment ligation at the replication fork and nucleotide excision repair (NER). DNA ligase IV (LigIV) mediates repair of DNA double strand br...

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Detalles Bibliográficos
Autores principales:	Arakawa, Hiroshi, Bednar, Theresa, Wang, Minli, Paul, Katja, Mladenov, Emil, Bencsik-Theilen, Alena A., Iliakis, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315315/ https://www.ncbi.nlm.nih.gov/pubmed/22127868 http://dx.doi.org/10.1093/nar/gkr1024

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