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mTOR signaling regulates the processing of pre-rRNA in human cells
Signaling through the mammalian target of rapamycin, complex 1 (mTORC1), positively regulates the transcription of ribosomal RNA (rRNA) and the synthesis of ribosomal proteins, thereby promoting the complex process of ribosome biogenesis. The major rRNAs are transcribed as a single precursor, which...
Autores principales: | Iadevaia, Valentina, Zhang, Ze, Jan, Eric, Proud, Christopher G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315323/ https://www.ncbi.nlm.nih.gov/pubmed/22121221 http://dx.doi.org/10.1093/nar/gkr1040 |
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