Cargando…

Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α

BACKGROUND: In addition to cytotoxic mechanisms directly impacting neurons, β-amyloid (Aβ)-induced glial activation also promotes release of proinflammatory molecules that may self-perpetuate reactive gliosis and damage neighbouring neurons, thus amplifying neuropathological lesions occurring in Alz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Scuderi, Caterina, Valenza, Marta, Stecca, Claudia, Esposito, Giuseppe, Carratù, Maria Rosaria, Steardo, Luca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315437/ https://www.ncbi.nlm.nih.gov/pubmed/22405189 http://dx.doi.org/10.1186/1742-2094-9-49

Ejemplares similares

Palmitoylethanolamide controls reactive gliosis and exerts neuroprotective functions in a rat model of Alzheimer's disease
por: Scuderi, C, et al.
Publicado: (2014)

Palmitoylethanolamide and White Matter Lesions: Evidence for Therapeutic Implications
por: Valenza, Marta, et al.
Publicado: (2022)

Co-Ultramicronized Palmitoylethanolamide/Luteolin Restores Oligodendrocyte Homeostasis via Peroxisome Proliferator-Activated Receptor-α in an In Vitro Model of Alzheimer’s Disease
por: Facchinetti, Roberta, et al.
Publicado: (2022)

Palmitoylethanolamide counteracts reactive astrogliosis induced by β-amyloid peptide
por: Scuderi, Caterina, et al.
Publicado: (2011)

Neuroprotective effects of mild hypoxia in organotypic hippocampal slice cultures
por: Kim, Seh Hyun, et al.
Publicado: (2015)

Ultramicronized palmitoylethanolamide rescues learning and memory impairments in a triple transgenic mouse model of Alzheimer’s disease by exerting anti-inflammatory and neuroprotective effects
por: Scuderi, Caterina, et al.
Publicado: (2018)

Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement
por: Esposito, Giuseppe, et al.
Publicado: (2011)

Palmitoylethanolamide Dampens Reactive Astrogliosis and Improves Neuronal Trophic Support in a Triple Transgenic Model of Alzheimer's Disease: In Vitro and In Vivo Evidence
por: Bronzuoli, Maria Rosanna, et al.
Publicado: (2018)

Looking for a Treatment for the Early Stage of Alzheimer’s Disease: Preclinical Evidence with Co-Ultramicronized Palmitoylethanolamide and Luteolin
por: Facchinetti, Roberta, et al.
Publicado: (2020)

Nimodipine Exerts Time-Dependent Neuroprotective Effect after Excitotoxical Damage in Organotypic Slice Cultures
por: Hohmann, Urszula, et al.
Publicado: (2022)

Neuroprotective Effects of α-Tocotrienol on Kainic Acid-Induced Neurotoxicity in Organotypic Hippocampal Slice Cultures
por: Jung, Na Young, et al.
Publicado: (2013)

Organotypic hippocampal slices, an emerging tool to model synucleinopathies
por: Elfarrash, Sara, et al.
Publicado: (2020)

The neuroprotective role of microglial cells against amyloid beta‐mediated toxicity in organotypic hippocampal slice cultures
por: Richter, Maren, et al.
Publicado: (2020)

Persistent Gliosis Interferes with Neurogenesis in Organotypic Hippocampal Slice Cultures
por: Gerlach, Johannes, et al.
Publicado: (2016)

The Impact of Chemical Fixation on the Microanatomy of Mouse Organotypic Hippocampal Slices
por: Idziak, Agata, et al.
Publicado: (2023)

Nanocapsules with Polyelectrolyte Shell as a Platform for 1,25-dihydroxyvitamin D3 Neuroprotection: Study in Organotypic Hippocampal Slices
por: Ślusarczyk, Joanna, et al.
Publicado: (2016)

A hierarchy of manganese competition and entry in organotypic hippocampal slice cultures
por: Petrus, Emily, et al.
Publicado: (2021)

β-Adrenoceptor activation depresses brain inflammation and is neuroprotective in lipopolysaccharide-induced sensitization to oxygen-glucose deprivation in organotypic hippocampal slices
por: Markus, Tina, et al.
Publicado: (2010)

Neuroprotective Activities of Palmitoylethanolamide in an Animal Model of Parkinson's Disease
por: Esposito, Emanuela, et al.
Publicado: (2012)

Inflammatory and cytotoxic effects of bifenthrin in primary microglia and organotypic hippocampal slice cultures
por: Gargouri, Brahim, et al.
Publicado: (2018)

Acute death of astrocytes in blast-exposed rat organotypic hippocampal slice cultures
por: Miller, Anna P., et al.
Publicado: (2017)

Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture
por: Hoyle, Christopher, et al.
Publicado: (2020)

Systemic Inflammation and Astrocyte Reactivity in the Neuropsychiatric Sequelae of COVID-19: Focus on Autism Spectrum Disorders
por: Valenza, Marta, et al.
Publicado: (2021)

Altered Waste Disposal System in Aging and Alzheimer’s Disease: Focus on Astrocytic Aquaporin-4
por: Valenza, Marta, et al.
Publicado: (2020)

Effects of Blast Overpressure on Neurons and Glial Cells in Rat Organotypic Hippocampal Slice Cultures
por: Miller, Anna P., et al.
Publicado: (2015)

Desflurane impairs outcome of organotypic hippocampal slices in an in vitro model of traumatic brain injury
por: Krings, Matthias, et al.
Publicado: (2016)

Intrinsic Inflammation Is a Potential Anti-Epileptogenic Target in the Organotypic Hippocampal Slice Model
por: Chong, Seon-Ah, et al.
Publicado: (2018)

A new method allowing long‐term potentiation recordings in hippocampal organotypic slices
por: Paci, Paula, et al.
Publicado: (2017)

Using organotypic hippocampal slice cultures to gain insight into mechanisms responsible for the neuroprotective effects of meloxicam: a role for gamma aminobutyric and endoplasmic reticulum stress
por: Landucci, Elisa, et al.
Publicado: (2019)

Development of P301S tau seeded organotypic hippocampal slice cultures to study potential therapeutics
por: McCarthy, James M., et al.
Publicado: (2021)

Impact of age-related neuroglial cell responses on hippocampal deterioration
por: Ojo, Joseph O., et al.
Publicado: (2015)

Neuroprotective Potential and Paracrine Activity of Stromal Vs. Culture-Expanded hMSC Derived from Wharton Jelly under Co-Cultured with Hippocampal Organotypic Slices
por: Dabrowska, Sylwia, et al.
Publicado: (2017)

Alternative Targets to Fight Alzheimer’s Disease: Focus on Astrocytes
por: Valenza, Marta, et al.
Publicado: (2021)

ORGANOTYPIC BRAIN SLICE CULTURES: A REVIEW
por: HUMPEL, C.
Publicado: (2015)

Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model
por: Healy, Sinead, et al.
Publicado: (2016)

The hyperexcitability of dentate granule neurons in organotypic hippocampal slice cultures is due to reorganization of synaptic inputs in vitro
por: Gilbride, Charlie J.
Publicado: (2016)

Differential Cannabinoid Receptor Expression during Reactive Gliosis: a Possible Implication for a Nonpsychotropic Neuroprotection
por: De Filippis, Daniele, et al.
Publicado: (2009)

A refined in vitro model to study inflammatory responses in organotypic membrane culture of postnatal rat hippocampal slices
por: Huuskonen, Jari, et al.
Publicado: (2005)

Multiple Single-Unit Long-Term Tracking on Organotypic Hippocampal Slices Using High-Density Microelectrode Arrays
por: Gong, Wei, et al.
Publicado: (2016)

Biocompatibility of very small superparamagnetic iron oxide nanoparticles in murine organotypic hippocampal slice cultures and the role of microglia
por: Pohland, Martin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_n0rhr0esrdcc1081dqpoh50udo