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Igf1r Signaling Is Indispensable for Preimplantation Development and Is Activated via a Novel Function of E-cadherin

Insulin-like growth factor I receptor (Igf1r) signaling controls proliferation, differentiation, growth, and cell survival in many tissues; and its deregulated activity is involved in tumorigenesis. Although important during fetal growth and postnatal life, a function for the Igf pathway during prei...

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Detalles Bibliográficos
Autores principales: Bedzhov, Ivan, Liszewska, Ewa, Kanzler, Benoît, Stemmler, Marc P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315466/
https://www.ncbi.nlm.nih.gov/pubmed/22479204
http://dx.doi.org/10.1371/journal.pgen.1002609