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Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals

Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are highly heritable and are inversely associated with type 2 diabetes mellitus (T2D) and other metabolic traits. We conducted a meta-analysis of genome-wide association studies in 39,883 individuals of European ances...

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Detalles Bibliográficos
Autores principales: Dastani, Zari, Hivert, Marie-France, Timpson, Nicholas, Perry, John R. B., Yuan, Xin, Scott, Robert A., Henneman, Peter, Heid, Iris M., Kizer, Jorge R., Lyytikäinen, Leo-Pekka, Fuchsberger, Christian, Tanaka, Toshiko, Morris, Andrew P., Small, Kerrin, Isaacs, Aaron, Beekman, Marian, Coassin, Stefan, Lohman, Kurt, Qi, Lu, Kanoni, Stavroula, Pankow, James S., Uh, Hae-Won, Wu, Ying, Bidulescu, Aurelian, Rasmussen-Torvik, Laura J., Greenwood, Celia M. T., Ladouceur, Martin, Grimsby, Jonna, Manning, Alisa K., Liu, Ching-Ti, Kooner, Jaspal, Mooser, Vincent E., Vollenweider, Peter, Kapur, Karen A., Chambers, John, Wareham, Nicholas J., Langenberg, Claudia, Frants, Rune, Willems-vanDijk, Ko, Oostra, Ben A., Willems, Sara M., Lamina, Claudia, Winkler, Thomas W., Psaty, Bruce M., Tracy, Russell P., Brody, Jennifer, Chen, Ida, Viikari, Jorma, Kähönen, Mika, Pramstaller, Peter P., Evans, David M., St. Pourcain, Beate, Sattar, Naveed, Wood, Andrew R., Bandinelli, Stefania, Carlson, Olga D., Egan, Josephine M., Böhringer, Stefan, van Heemst, Diana, Kedenko, Lyudmyla, Kristiansson, Kati, Nuotio, Marja-Liisa, Loo, Britt-Marie, Harris, Tamara, Garcia, Melissa, Kanaya, Alka, Haun, Margot, Klopp, Norman, Wichmann, H.-Erich, Deloukas, Panos, Katsareli, Efi, Couper, David J., Duncan, Bruce B., Kloppenburg, Margreet, Adair, Linda S., Borja, Judith B., Wilson, James G., Musani, Solomon, Guo, Xiuqing, Johnson, Toby, Semple, Robert, Teslovich, Tanya M., Allison, Matthew A., Redline, Susan, Buxbaum, Sarah G., Mohlke, Karen L., Meulenbelt, Ingrid, Ballantyne, Christie M., Dedoussis, George V., Hu, Frank B., Liu, Yongmei, Paulweber, Bernhard, Spector, Timothy D., Slagboom, P. Eline, Ferrucci, Luigi, Jula, Antti, Perola, Markus, Raitakari, Olli, Florez, Jose C., Salomaa, Veikko, Eriksson, Johan G., Frayling, Timothy M., Hicks, Andrew A., Lehtimäki, Terho, Smith, George Davey, Siscovick, David S., Kronenberg, Florian, van Duijn, Cornelia, Loos, Ruth J. F., Waterworth, Dawn M., Meigs, James B., Dupuis, Josee, Richards, J. Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315470/
https://www.ncbi.nlm.nih.gov/pubmed/22479202
http://dx.doi.org/10.1371/journal.pgen.1002607

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