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Accurate Prediction of Inducible Transcription Factor Binding Intensities In Vivo

DNA sequence and local chromatin landscape act jointly to determine transcription factor (TF) binding intensity profiles. To disentangle these influences, we developed an experimental approach, called protein/DNA binding followed by high-throughput sequencing (PB–seq), that allows the binding energy...

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Detalles Bibliográficos
Autores principales:	Guertin, Michael J., Martins, André L., Siepel, Adam, Lis, John T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315474/ https://www.ncbi.nlm.nih.gov/pubmed/22479205 http://dx.doi.org/10.1371/journal.pgen.1002610

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