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Drosophila muscleblind Codes for Proteins with One and Two Tandem Zinc Finger Motifs
Muscleblind-like proteins, Muscleblind (Mbl) in Drosophila and MBNL1-3 in vertebrates, are regulators of alternative splicing. Human MBNL1 is a key factor in the etiology of myotonic dystrophy (DM), a muscle wasting disease caused by the occurrence of toxic RNA molecules containing CUG/CCUG repeats....
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315501/ https://www.ncbi.nlm.nih.gov/pubmed/22479576 http://dx.doi.org/10.1371/journal.pone.0034248 |