Bak Compensated for Bax in p53-null Cells to Release Cytochrome c for the Initiation of Mitochondrial Signaling during Withanolide D-Induced Apoptosis

The goal of cancer chemotherapy to induce multi-directional apoptosis as targeting a single pathway is unable to decrease all the downstream effect arises from crosstalk. Present study reports that Withanolide D (WithaD), a steroidal lactone isolated from Withania somnifera, induced cellular apoptos...

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Detalles Bibliográficos
Autores principales: Mondal, Susmita, Bhattacharya, Kaushik, Mallick, Asish, Sangwan, Rajender, Mandal, Chitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315518/
https://www.ncbi.nlm.nih.gov/pubmed/22479585
http://dx.doi.org/10.1371/journal.pone.0034277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315518/
https://www.ncbi.nlm.nih.gov/pubmed/22479585
http://dx.doi.org/10.1371/journal.pone.0034277

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