xQTL workbench: a scalable web environment for multi-level QTL analysis

Summary: xQTL workbench is a scalable web platform for the mapping of quantitative trait loci (QTLs) at multiple levels: for example gene expression (eQTL), protein abundance (pQTL), metabolite abundance (mQTL) and phenotype (phQTL) data. Popular QTL mapping methods for model organism and human popu...

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Autores principales: Arends, Danny, van der Velde, K. Joeri, Prins, Pjotr, Broman, Karl W., Möller, Steffen, Jansen, Ritsert C., Swertz, Morris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315722/
https://www.ncbi.nlm.nih.gov/pubmed/22308096
http://dx.doi.org/10.1093/bioinformatics/bts049
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author Arends, Danny
van der Velde, K. Joeri
Prins, Pjotr
Broman, Karl W.
Möller, Steffen
Jansen, Ritsert C.
Swertz, Morris A.
author_facet Arends, Danny
van der Velde, K. Joeri
Prins, Pjotr
Broman, Karl W.
Möller, Steffen
Jansen, Ritsert C.
Swertz, Morris A.
author_sort Arends, Danny
collection PubMed
description Summary: xQTL workbench is a scalable web platform for the mapping of quantitative trait loci (QTLs) at multiple levels: for example gene expression (eQTL), protein abundance (pQTL), metabolite abundance (mQTL) and phenotype (phQTL) data. Popular QTL mapping methods for model organism and human populations are accessible via the web user interface. Large calculations scale easily on to multi-core computers, clusters and Cloud. All data involved can be uploaded and queried online: markers, genotypes, microarrays, NGS, LC-MS, GC-MS, NMR, etc. When new data types come available, xQTL workbench is quickly customized using the Molgenis software generator. Availability: xQTL workbench runs on all common platforms, including Linux, Mac OS X and Windows. An online demo system, installation guide, tutorials, software and source code are available under the LGPL3 license from http://www.xqtl.org. Contact: m.a.swertz@rug.nl
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spelling pubmed-33157222012-03-30 xQTL workbench: a scalable web environment for multi-level QTL analysis Arends, Danny van der Velde, K. Joeri Prins, Pjotr Broman, Karl W. Möller, Steffen Jansen, Ritsert C. Swertz, Morris A. Bioinformatics Applications Note Summary: xQTL workbench is a scalable web platform for the mapping of quantitative trait loci (QTLs) at multiple levels: for example gene expression (eQTL), protein abundance (pQTL), metabolite abundance (mQTL) and phenotype (phQTL) data. Popular QTL mapping methods for model organism and human populations are accessible via the web user interface. Large calculations scale easily on to multi-core computers, clusters and Cloud. All data involved can be uploaded and queried online: markers, genotypes, microarrays, NGS, LC-MS, GC-MS, NMR, etc. When new data types come available, xQTL workbench is quickly customized using the Molgenis software generator. Availability: xQTL workbench runs on all common platforms, including Linux, Mac OS X and Windows. An online demo system, installation guide, tutorials, software and source code are available under the LGPL3 license from http://www.xqtl.org. Contact: m.a.swertz@rug.nl Oxford University Press 2012-04-01 2012-02-03 /pmc/articles/PMC3315722/ /pubmed/22308096 http://dx.doi.org/10.1093/bioinformatics/bts049 Text en © The Author(s) 2012. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Note
Arends, Danny
van der Velde, K. Joeri
Prins, Pjotr
Broman, Karl W.
Möller, Steffen
Jansen, Ritsert C.
Swertz, Morris A.
xQTL workbench: a scalable web environment for multi-level QTL analysis
title xQTL workbench: a scalable web environment for multi-level QTL analysis
title_full xQTL workbench: a scalable web environment for multi-level QTL analysis
title_fullStr xQTL workbench: a scalable web environment for multi-level QTL analysis
title_full_unstemmed xQTL workbench: a scalable web environment for multi-level QTL analysis
title_short xQTL workbench: a scalable web environment for multi-level QTL analysis
title_sort xqtl workbench: a scalable web environment for multi-level qtl analysis
topic Applications Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315722/
https://www.ncbi.nlm.nih.gov/pubmed/22308096
http://dx.doi.org/10.1093/bioinformatics/bts049
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