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Phosphoinositide lipid phosphatase SHIP1 and PTEN coordinate to regulate cell migration and adhesion

The second messenger phosphatidylinositol(3,4,5)P(3) (PtdIns(3,4,5)P(3)) is formed by stimulation of various receptors, including G protein–coupled receptors and integrins. The lipid phosphatases PTEN and SHIP1 are critical in regulating the level of PtdIns(3,4,5)P(3) during chemotaxis. Observations...

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Detalles Bibliográficos
Autores principales:	Mondal, Subhanjan, Subramanian, Kulandayan K., Sakai, Jiro, Bajrami, Besnik, Luo, Hongbo R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315799/ https://www.ncbi.nlm.nih.gov/pubmed/22323291 http://dx.doi.org/10.1091/mbc.E11-10-0889

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