Cargando…
MAL facilitates the incorporation of exocytic uroplakin-delivering vesicles into the apical membrane of urothelial umbrella cells
The apical surface of mammalian bladder urothelium is covered by large (500–1000 nm) two-dimensional (2D) crystals of hexagonally packed 16-nm uroplakin particles (urothelial plaques), which play a role in permeability barrier function and uropathogenic bacterial binding. How the uroplakin proteins...
Autores principales: | Zhou, Ge, Liang, Feng-Xia, Romih, Rok, Wang, Zefang, Liao, Yi, Ghiso, Jorge, Luque-Garcia, Jose L., Neubert, Thomas A., Kreibich, Gert, Alonso, Miguel A., Schaeren-Wiemers, Nicole, Sun, Tung-Tien |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315800/ https://www.ncbi.nlm.nih.gov/pubmed/22323295 http://dx.doi.org/10.1091/mbc.E11-09-0823 |
Ejemplares similares
-
Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells
por: Wankel, Bret, et al.
Publicado: (2016) -
Uroplakin IIIb, a urothelial differentiation marker, dimerizes with uroplakin Ib as an early step of urothelial plaque assembly
por: Deng, Fang-Ming, et al.
Publicado: (2002) -
SNX31: A Novel Sorting Nexin Associated with the Uroplakin-Degrading Multivesicular Bodies in Terminally Differentiated Urothelial Cells
por: Vieira, Neide, et al.
Publicado: (2014) -
Heterogeneity of uroplakin localization in human normal urothelium, papilloma and papillary carcinoma
por: Zupancic, Dasa, et al.
Publicado: (2013) -
Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases
por: Kong, Xiang-Tian, et al.
Publicado: (2004)