EGFR-dependent phosphorylation of leucine-rich repeat kinase LRRK1 is important for proper endosomal trafficking of EGFR

Ligand-induced activation of the epidermal growth factor receptor (EGFR) initiates trafficking events that relocalize the receptors from the cell surface to intracellular endocytic compartments. We recently reported that leucine-rich repeat kinase 1 (LRRK1) is involved in the trafficking of EGFR fro...

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Detalles Bibliográficos
Autores principales: Ishikawa, Kouki, Nara, Atsuki, Matsumoto, Kunihiro, Hanafusa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315817/
https://www.ncbi.nlm.nih.gov/pubmed/22337768
http://dx.doi.org/10.1091/mbc.E11-09-0780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315817/
https://www.ncbi.nlm.nih.gov/pubmed/22337768
http://dx.doi.org/10.1091/mbc.E11-09-0780

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