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EGFR-dependent phosphorylation of leucine-rich repeat kinase LRRK1 is important for proper endosomal trafficking of EGFR
Ligand-induced activation of the epidermal growth factor receptor (EGFR) initiates trafficking events that relocalize the receptors from the cell surface to intracellular endocytic compartments. We recently reported that leucine-rich repeat kinase 1 (LRRK1) is involved in the trafficking of EGFR fro...
Autores principales: | Ishikawa, Kouki, Nara, Atsuki, Matsumoto, Kunihiro, Hanafusa, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315817/ https://www.ncbi.nlm.nih.gov/pubmed/22337768 http://dx.doi.org/10.1091/mbc.E11-09-0780 |
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