Cargando…

The immunoglobulin CH1 constant region modulates antigen binding affinity and functional activities of the broadly neutralizing 2F5 HIV specific antibody

Detalles Bibliográficos
Autores principales:	Tudor, Daniela, Drillet, Anne-Sophie, Schwartz-Cornil, Isabelle, Shen, Ruizhong, Smith, Phillip D, Bomsel, Morgane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315950/ http://dx.doi.org/10.1186/1742-4690-7-S1-P23

Ejemplares similares

Calcitonin gene–related peptide inhibits Langerhans cell–mediated HIV-1 transmission
por: Ganor, Yonatan, et al.
Publicado: (2013)

The Protective HIV-1 Envelope gp41 Antigen P1 Acts as a Mucosal Adjuvant Stimulating the Innate Immunity
por: Xu, Lin, et al.
Publicado: (2021)

P11-20. HIV-1 gp41-specific mucosal IgAs from highly exposed but IgG seronegative women block HIV-1 epithelial transcytosis and neutralize CD4+ cell infection
por: Tudor, D, et al.
Publicado: (2009)

Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies
por: LaBranche, Celia C., et al.
Publicado: (2019)

The CH1α domain of mucosal gp41 IgA contributes to antibody specificity and antiviral functions in HIV-1 highly exposed Sero-Negative individuals
por: Khamassi, Marwa, et al.
Publicado: (2020)

Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies
por: LaBranche, Celia C., et al.
Publicado: (2019)

A Nonparametric Procedure for Defining a New Humoral Immunologic Profile in a Pilot Study on HIV Infected Patients
por: Brombin, Chiara, et al.
Publicado: (2013)

Key mutations stabilize antigen-binding conformation during affinity maturation of a broadly neutralizing influenza antibody lineage
por: Xu, Huafeng, et al.
Publicado: (2015)

Antibody Fc-chimerism and effector functions: When IgG takes advantage of IgA
por: Cottignies-Calamarte, Andréa, et al.
Publicado: (2023)

Binding affinity landscapes constrain the evolution of broadly neutralizing anti-influenza antibodies
por: Phillips, Angela M, et al.
Publicado: (2021)

Multiscale affinity maturation simulations to elicit broadly neutralizing antibodies against HIV
por: Conti, Simone, et al.
Publicado: (2022)

Alpha6beta1 integrin expressed by sperm is determinant in mouse fertilization
por: Barraud-Lange, Virginie, et al.
Publicado: (2007)

IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates
por: Logerot, Sandrine, et al.
Publicado: (2021)

Affinity maturation pathway of an anti-MPER neutralizing mAb, CAP206-CH12
por: Tumba, NL, et al.
Publicado: (2012)

Antibody-Dependent Cellular Phagocytosis of HIV-1-Infected Cells Is Efficiently Triggered by IgA Targeting HIV-1 Envelope Subunit gp41
por: Duchemin, Maxence, et al.
Publicado: (2020)

Designer antigens for elicitation of broadly neutralizing antibodies against HIV
por: Kok, Tuckweng, et al.
Publicado: (2014)

Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets
por: Ching, Kathryn H., et al.
Publicado: (2017)

IgA Targeting Human Immunodeficiency Virus-1 Envelope gp41 Triggers Antibody-Dependent Cellular Cytotoxicity Cross-Clade and Cooperates with gp41-Specific IgG to Increase Cell Lysis
por: Duchemin, Maxence, et al.
Publicado: (2018)

Design of an HIV Env antigen that binds with high affinity to antibodies against linear, conformational and broadly neutralizing epitopes within V1/V2
por: Liao, L, et al.
Publicado: (2012)

A constant affinity threshold for T cell tolerance
por: Naeher, Dieter, et al.
Publicado: (2007)

Isotype switching: Mouse IgG3 constant region drives increased affinity for polysaccharide antigens
por: Harmer, Nicholas J., et al.
Publicado: (2016)

Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection
por: Muenchhoff, M., et al.
Publicado: (2020)

Development of broadly neutralizing antibodies targeting the cytomegalovirus subdominant antigen gH
por: Parsons, Andrea J., et al.
Publicado: (2022)

HIV-1 cell-to-cell transmission and broadly neutralizing antibodies
por: Dufloo, Jérémy, et al.
Publicado: (2018)

Peptide P5 (residues 628–683), comprising the entire membrane proximal region of HIV-1 gp41 and its calcium-binding site, is a potent inhibitor of HIV-1 infection
por: Yu, Huifeng, et al.
Publicado: (2008)

Identification of variant HIV envelope proteins with enhanced affinities for precursors to anti-gp41 broadly neutralizing antibodies
por: Zhu, Hong, et al.
Publicado: (2019)

Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01
por: Pinto, Dora, et al.
Publicado: (2019)

Artificial Affinity Proteins as Ligands of Immunoglobulins
por: Mouratou, Barbara, et al.
Publicado: (2015)

Exchanging Murine and Human Immunoglobulin Constant Chains Affects the Kinetics and Thermodynamics of Antigen Binding and Chimeric Antibody Autoreactivity
por: Torres, Marcela, et al.
Publicado: (2007)

Selection of immunoglobulin elbow region mutations impacts interdomain conformational flexibility in HIV-1 broadly neutralizing antibodies
por: Henderson, Rory, et al.
Publicado: (2019)

Entry of viruses through the epithelial barrier: pathogenic trickery
por: Bomsel, Morgane, et al.
Publicado: (2003)

Editorial: Mucosal immunity to HIV and SARS-CoV-2 infection and vaccination
por: Bomsel, Morgane, et al.
Publicado: (2023)

Determination of Rate Constants and Equilibrium Constants for Solution-Phase Drug–Protein Interactions by Ultrafast Affinity Extraction
por: Zheng, Xiwei, et al.
Publicado: (2014)

Rate and affinity binding constants determined by SPR spectroscopy reveal differential antigenicity of HIV gp120 and gp140
por: Gearhart, TL, et al.
Publicado: (2012)

Stapled HIV-1 Peptides Recapitulate Antigenic Structures and Engage Broadly Neutralizing Antibodies
por: Bird, Gregory H., et al.
Publicado: (2014)

Specific Residue Interactions Regulate the Binding of Dengue Antigens to Broadly Neutralizing EDE Antibodies
por: Lapelosa, Mauro, et al.
Publicado: (2018)

The Effects of Framework Mutations at the Variable Domain Interface on Antibody Affinity Maturation in an HIV-1 Broadly Neutralizing Antibody Lineage
por: Zhou, Jeffrey O., et al.
Publicado: (2020)

A broad diversity in oxygen affinity to haemoglobin
por: Balcerek, Björn, et al.
Publicado: (2020)

Determination of the affinity constants for phage display albumin-binding peptides
por: Shi, Yi-Feng
Publicado: (2023)

P19-02. High protection of female macaques from repeated intravaginal challenges with SHIV-162P3 upon mucosal vaccination with Gp41 subunits-virosomes
por: Bomsel, M, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_7ls0s8pvcoch8rlvqbi06o7g55