Cargando…

Allosteric regulation by non peptidic, low molecular weight compounds of CCR5 coupling to g-proteins and interaction with Gp120 - consequences on inhibition of R5 HIV-1 infection

Detalles Bibliográficos
Autores principales:	Rueda, Patricia, Garcia-Perez, Javier, Staropoli, Isabelle, Kellenberger, Esther, Alcami, José, Arenzana-Seisdedos, Fernando, Lagane, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316099/ http://dx.doi.org/10.1186/1742-4690-7-S1-P163

Ejemplares similares

Modeling of CCR5 Recognition by HIV-1 gp120: How the Viral Protein Exploits the Conformational Plasticity of the Coreceptor
por: Jacquemard, Célien, et al.
Publicado: (2021)

A single-residue change in the HIV-1 V3 loop associated with maraviroc resistance impairs CCR5 binding affinity while increasing replicative capacity
por: Garcia-Perez, Javier, et al.
Publicado: (2015)

CCR5 structural plasticity shapes HIV-1 phenotypic properties
por: Colin, Philippe, et al.
Publicado: (2018)

Molecular Recognition of CCR5 by an HIV-1 gp120 V3 Loop
por: Tamamis, Phanourios, et al.
Publicado: (2014)

The first structure of HIV-1 gp120 with CD4 and CCR5 receptors
por: Guan, Yongjun
Publicado: (2019)

Tracking receptor motions at the plasma membrane reveals distinct effects of ligands on CCR5 dynamics depending on its dimerization status
por: Momboisse, Fanny, et al.
Publicado: (2022)

Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction
por: Grainger, David J, et al.
Publicado: (2005)

Short Communication: HIV-1 Variants That Use Mouse CCR5 Reveal Critical Interactions of gp120's V3 Crown with CCR5 Extracellular Loop 1
por: Platt, Emily J., et al.
Publicado: (2015)

Staphylococcus aureus Leukocidin LukED and HIV-1 gp120 Target Different Sequence Determinants on CCR5
por: Tam, Kayan, et al.
Publicado: (2016)

Allosteric induction of the CD4-bound conformation of HIV-1 Gp120
por: Roitburd-Berman, Anna, et al.
Publicado: (2013)

Allosteric Modulation of the HIV-1 gp120-gp41 Association Site by Adjacent gp120 Variable Region 1 (V1) N-Glycans Linked to Neutralization Sensitivity
por: Drummer, Heidi E., et al.
Publicado: (2013)

Estimating the Threshold Surface Density of Gp120-CCR5 Complexes Necessary for HIV-1 Envelope-Mediated Cell-Cell Fusion
por: Mulampaka, Shiva Naresh, et al.
Publicado: (2011)

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS
por: Sterjovski, Jasminka, et al.
Publicado: (2007)

The CXCL12γ Chemokine Displays Unprecedented Structural and Functional Properties that Make It a Paradigm of Chemoattractant Proteins
por: Rueda, Patricia, et al.
Publicado: (2008)

The C5 region of HIV-1 gp120 binds specific
por: Dalgleish, A, et al.
Publicado: (2006)

Interaction of Chemokine Receptor CCR5 with its Ligands: Multiple Domains for HIV-1 gp120 Binding and a Single Domain for Chemokine Binding
por: Wu, Lijun, et al.
Publicado: (1997)

Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands
por: Zhou, Zhicheng, et al.
Publicado: (2023)

Targeting CCR5 trafficking to inhibit HIV-1 infection
por: Boncompain, Gaelle, et al.
Publicado: (2019)

A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations
por: Roche, Michael, et al.
Publicado: (2013)

Chemokine Co-Receptor CCR5/CXCR4-Dependent Modulation of Kv2.1 Channel Confers Acute Neuroprotection to HIV-1 Glycoprotein gp120 Exposure
por: Shepherd, Andrew J., et al.
Publicado: (2013)

Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis
por: Armani-Tourret, Marie, et al.
Publicado: (2021)

Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism
por: Smith, Lisa K., et al.
Publicado: (2021)

Physiological Corticosterone Attenuates gp120-Mediated Microglial Activation and Is Associated with Reduced Anxiety-Like Behavior in gp120-Expressing Mice
por: Moss, Emaya M., et al.
Publicado: (2023)

Disruption of the cholinergic anti-inflammatory response by R5-tropic HIV-1 protein gp120(JRFL)
por: Ríos, Sonnieliz Cotto, et al.
Publicado: (2021)

The HIV-1 Gp120/CXCR4 Axis Promotes CCR7 Ligand-Dependent CD4 T Cell Migration: CCR7 Homo- and CCR7/CXCR4 Hetero-Oligomer Formation as a Possible Mechanism for Up-Regulation of Functional CCR7
por: Hayasaka, Haruko, et al.
Publicado: (2015)

Eliciting neutralizing antibodies with gp120 outer domain
por: Qin, Y, et al.
Publicado: (2012)

Internalization and Axonal Transport of the HIV Glycoprotein gp120
por: Berth, Sarah, et al.
Publicado: (2015)

SDF-1/CXCL12: A Chemokine in the Life Cycle of HIV
por: Arenzana-Seisdedos, Fernando
Publicado: (2015)

Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 ± IL-15
por: McKee, Hayley J, et al.
Publicado: (2004)

Development of Protein- and Peptide-Based HIV Entry Inhibitors Targeting gp120 or gp41
por: Pu, Jing, et al.
Publicado: (2019)

Convergent HIV-1 Evolution upon Targeted Destabilization of the gp120-gp41 Interface
por: Torrents de la Peña, Alba, et al.
Publicado: (2021)

Cholesterol Is a Dose-Dependent Positive Allosteric Modulator of CCR3 Ligand Affinity and G Protein Coupling
por: van Aalst, Evan, et al.
Publicado: (2021)

Enhancement of Chemokine Function as an Immunomodulatory Strategy Employed by Human Herpesviruses
por: Viejo-Borbolla, Abel, et al.
Publicado: (2012)

NMR spectroscopy of HIV-1 gp120 outer domain
por: Sastry, M, et al.
Publicado: (2012)

Behavioral Evidence for a Tau and HIV-gp120 Interaction
por: Vijayan, Murali, et al.
Publicado: (2022)

Structural Basis for Species Selectivity in the HIV-1 gp120-CD4 Interaction: Restoring Affinity to gp120 in Murine CD4 Mimetic Peptides
por: Kassler, Kristin, et al.
Publicado: (2011)

Evolution of the HIV-1 envelope glycoproteins with a disulfide bond between gp120 and gp41
por: Sanders, Rogier W, et al.
Publicado: (2004)

CCR5 saves lives
por: Van Epps, Heather L.
Publicado: (2005)

Antibodies to the CD4-binding site of HIV-1 gp120 suppress gp120-specific CD4 T cell response while enhancing antibody response
por: Visciano, Maria Luisa, et al.
Publicado: (2008)

Interaction of the gp120 V1V2 loop with a neighboring gp120 unit shields the HIV envelope trimer against cross-neutralizing antibodies
por: Rusert, Peter, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_kjp5gsn4s6g1k59rcqlmm4ko1i