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The resistance of intracellular mediators to doxorubicin and cisplatin are distinct in 3D and 2D endometrial cancer

BACKGROUND: Advanced endometrial cancer often shows resistance to clinical chemotherapy although potencies of anticancer drugs in vitro are promising. The disparity suggests that in vivo microenvironments are not recapitulated by in vitro models used for preclinical testing. However, spheroids repli...

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Detalles Bibliográficos
Autores principales:	Chitcholtan, Kenny, Sykes, Peter H, Evans, John J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316127/ https://www.ncbi.nlm.nih.gov/pubmed/22394685 http://dx.doi.org/10.1186/1479-5876-10-38

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