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Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage

BACKGROUND: The DNA-dependent protein kinase (DNA-PK) is a nuclear complex composed of a large catalytic subunit (DNA-PKcs) and a heterodimeric DNA-targeting subunit Ku. DNA-PK is a major component of the non-homologous end-joining (NHEJ) repair mechanism, which is activated in the presence of DNA d...

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Detalles Bibliográficos
Autores principales:	Olsen, Birgitte B, Wang, Shih-Ya, Svenstrup, Tina H, Chen, Benjamin PC, Guerra, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316135/ https://www.ncbi.nlm.nih.gov/pubmed/22404984 http://dx.doi.org/10.1186/1471-2199-13-7

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