Synchronous Occurrence of Papillary Carcinoma in the Thyroid Gland and Thyroglossal Duct in an Adolescent with Congenital Hypothyroidism

Thyroid carcinoma (TC) combined with congenital hypothyroidism is rare. The synchronous occurrence of these two conditions is even rarer. We describe a patient with congenital hypothyroidism in whom hyperthyroglobulinemia and nodules developed despite adequate replacement therapy. Papillary TC was d...

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Autores principales: Şıklar, Zeynep, Berberoğlu, Merih, Yağmurlu, Aydın, Hacıhamdioğlu, Bülent, Savaş Erdeve, Şenay, Fitöz, Suat, Kır, Metin, Öçal, Gönül
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2012
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316460/
https://www.ncbi.nlm.nih.gov/pubmed/22394702
http://dx.doi.org/10.4274/jcrpe.477
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author Şıklar, Zeynep
Berberoğlu, Merih
Yağmurlu, Aydın
Hacıhamdioğlu, Bülent
Savaş Erdeve, Şenay
Fitöz, Suat
Kır, Metin
Öçal, Gönül
author_facet Şıklar, Zeynep
Berberoğlu, Merih
Yağmurlu, Aydın
Hacıhamdioğlu, Bülent
Savaş Erdeve, Şenay
Fitöz, Suat
Kır, Metin
Öçal, Gönül
author_sort Şıklar, Zeynep
collection PubMed
description Thyroid carcinoma (TC) combined with congenital hypothyroidism is rare. The synchronous occurrence of these two conditions is even rarer. We describe a patient with congenital hypothyroidism in whom hyperthyroglobulinemia and nodules developed despite adequate replacement therapy. Papillary TC was detected at age 19 years. Postoperative diagnostic scintigraphy showed increased uptake in the thyroglossal duct region. Repetitive imaging of the thyroid gland can be useful in the early detection of TC in patients with congenital hypothyroidism. Moreover, this rare situation can be complicated by a synchronous thyroglossal duct carcinoma. Thyroglossal duct carcinoma can be detected if diagnostic scintigraphy is performed after total thyroidectomy. Conflict of interest:None declared.
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spelling pubmed-33164602012-04-10 Synchronous Occurrence of Papillary Carcinoma in the Thyroid Gland and Thyroglossal Duct in an Adolescent with Congenital Hypothyroidism Şıklar, Zeynep Berberoğlu, Merih Yağmurlu, Aydın Hacıhamdioğlu, Bülent Savaş Erdeve, Şenay Fitöz, Suat Kır, Metin Öçal, Gönül J Clin Res Pediatr Endocrinol Case Reports Thyroid carcinoma (TC) combined with congenital hypothyroidism is rare. The synchronous occurrence of these two conditions is even rarer. We describe a patient with congenital hypothyroidism in whom hyperthyroglobulinemia and nodules developed despite adequate replacement therapy. Papillary TC was detected at age 19 years. Postoperative diagnostic scintigraphy showed increased uptake in the thyroglossal duct region. Repetitive imaging of the thyroid gland can be useful in the early detection of TC in patients with congenital hypothyroidism. Moreover, this rare situation can be complicated by a synchronous thyroglossal duct carcinoma. Thyroglossal duct carcinoma can be detected if diagnostic scintigraphy is performed after total thyroidectomy. Conflict of interest:None declared. Galenos Publishing 2012-03 2012-03-08 /pmc/articles/PMC3316460/ /pubmed/22394702 http://dx.doi.org/10.4274/jcrpe.477 Text en © Journal of Clinical Research in Pediatric Endocrinology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Şıklar, Zeynep
Berberoğlu, Merih
Yağmurlu, Aydın
Hacıhamdioğlu, Bülent
Savaş Erdeve, Şenay
Fitöz, Suat
Kır, Metin
Öçal, Gönül
Synchronous Occurrence of Papillary Carcinoma in the Thyroid Gland and Thyroglossal Duct in an Adolescent with Congenital Hypothyroidism
title Synchronous Occurrence of Papillary Carcinoma in the Thyroid Gland and Thyroglossal Duct in an Adolescent with Congenital Hypothyroidism
title_full Synchronous Occurrence of Papillary Carcinoma in the Thyroid Gland and Thyroglossal Duct in an Adolescent with Congenital Hypothyroidism
title_fullStr Synchronous Occurrence of Papillary Carcinoma in the Thyroid Gland and Thyroglossal Duct in an Adolescent with Congenital Hypothyroidism
title_full_unstemmed Synchronous Occurrence of Papillary Carcinoma in the Thyroid Gland and Thyroglossal Duct in an Adolescent with Congenital Hypothyroidism
title_short Synchronous Occurrence of Papillary Carcinoma in the Thyroid Gland and Thyroglossal Duct in an Adolescent with Congenital Hypothyroidism
title_sort synchronous occurrence of papillary carcinoma in the thyroid gland and thyroglossal duct in an adolescent with congenital hypothyroidism
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316460/
https://www.ncbi.nlm.nih.gov/pubmed/22394702
http://dx.doi.org/10.4274/jcrpe.477
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