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Xylosyltransferase-I Regulates Glycosaminoglycan Synthesis during the Pathogenic Process of Human Osteoarthritis

Loss of glycosaminoglycan (GAG) chains of proteoglycans (PGs) is an early event of osteoarthritis (OA) resulting in cartilage degradation that has been previously demonstrated in both huma and experimental OA models. However, the mechanism of GAG loss and the role of xylosyltransferase-I (XT-I) that...

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Detalles Bibliográficos
Autores principales:	Venkatesan, Narayanan, Barré, Lydia, Bourhim, Mustapha, Magdalou, Jacques, Mainard, Didier, Netter, Patrick, Fournel-Gigleux, Sylvie, Ouzzine, Mohamed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316535/ https://www.ncbi.nlm.nih.gov/pubmed/22479506 http://dx.doi.org/10.1371/journal.pone.0034020

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