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Composition and Evolution of the Vertebrate and Mammalian Selenoproteomes

BACKGROUND: Selenium is an essential trace element in mammals due to its presence in proteins in the form of selenocysteine (Sec). Human genome codes for 25 Sec-containing protein genes, and mouse and rat genomes for 24. METHODOLOGY/PRINCIPAL FINDINGS: We characterized the selenoproteomes of 44 sequ...

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Detalles Bibliográficos
Autores principales: Mariotti, Marco, Ridge, Perry G., Zhang, Yan, Lobanov, Alexei V., Pringle, Thomas H., Guigo, Roderic, Hatfield, Dolph L., Gladyshev, Vadim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316567/
https://www.ncbi.nlm.nih.gov/pubmed/22479358
http://dx.doi.org/10.1371/journal.pone.0033066