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Cortactin Tyrosine Phosphorylation Promotes Its Deacetylation and Inhibits Cell Spreading
BACKGROUND: Cortactin is a classical Src kinase substrate that participates in actin cytoskeletal dynamics by activating the Arp2/3 complex and interacting with other regulatory proteins, including FAK. Cortactin has various domains that may contribute to the assembly of different protein platforms...
Autores principales: | Meiler, Eugenia, Nieto-Pelegrín, Elvira, Martinez-Quiles, Narcisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316595/ https://www.ncbi.nlm.nih.gov/pubmed/22479425 http://dx.doi.org/10.1371/journal.pone.0033662 |
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