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Molecular Dynamics Analysis of Apolipoprotein-D - Lipid Hydroperoxide Interactions: Mechanism for Selective Oxidation of Met-93
BACKGROUND: Recent studies suggest reduction of radical-propagating fatty acid hydroperoxides to inert hydroxides by interaction with apolipoprotein-D (apoD) Met93 may represent an antioxidant function for apoD. The nature and structural consequences of this selective interaction are unknown. METHOD...
Autores principales: | Oakley, Aaron J., Bhatia, Surabhi, Ecroyd, Heath, Garner, Brett |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316614/ https://www.ncbi.nlm.nih.gov/pubmed/22479522 http://dx.doi.org/10.1371/journal.pone.0034057 |
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