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Efficient iPS Cell Production with the MyoD Transactivation Domain in Serum-Free Culture
A major difficulty of producing induced pluripotent stem cells (iPSCs) has been the low efficiency of reprogramming differentiated cells into pluripotent cells. We previously showed that 5% of mouse embryonic fibroblasts (MEFs) were reprogrammed into iPSCs when they were transduced with a fusion gen...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316619/ https://www.ncbi.nlm.nih.gov/pubmed/22479546 http://dx.doi.org/10.1371/journal.pone.0034149 |