Proteasome Inhibitor Bortezomib Ameliorates Intestinal Injury in Mice

BACKGROUND: Bortezomib is a proteasome inhibitor that has shown impressive efficacy in the treatment of multiple myeloma. In mice, the addition of dextran sulfate sodium (DSS) to drinking water leads to acute colitis that can serve as an experimental animal model for human ulcerative colitis. METHOD...

Descripción completa

Detalles Bibliográficos
Autores principales: Yanaba, Koichi, Asano, Yoshihide, Tada, Yayoi, Sugaya, Makoto, Kadono, Takafumi, Sato, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316702/
https://www.ncbi.nlm.nih.gov/pubmed/22479648
http://dx.doi.org/10.1371/journal.pone.0034587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316702/
https://www.ncbi.nlm.nih.gov/pubmed/22479648
http://dx.doi.org/10.1371/journal.pone.0034587

Ejemplares similares