Cargando…
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis
BACKGROUND: A high circulating concentration of interleukin 6 is associated with increased risk of coronary heart disease. Blockade of the interleukin-6 receptor (IL6R) with a monoclonal antibody (tocilizumab) licensed for treatment of rheumatoid arthritis reduces systemic and articular inflammation...
| Formato: | Online Artículo Texto |
|---|---|
| Lenguaje: | English |
| Publicado: |
Elsevier
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316968/ https://www.ncbi.nlm.nih.gov/pubmed/22421340 http://dx.doi.org/10.1016/S0140-6736(12)60110-X |