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The Clinical and Prognostic Significance of Activated AKT-mTOR Pathway in Human Astrocytomas

Astrocytomas, the most common type of gliomas, and especially grade IV glioblastomas are “endowed” with strong proliferation and invasion potentials, high recurrence rate, and poor patients' prognosis. Aberrant signaling of AKT-mTOR (mammalian target of rapamycin) has been implicated in carcino...

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Detalles Bibliográficos
Autores principales:	El Habr, Elias A., Adamopoulos, Christos, Levidou, Georgia, Saetta, Aggeliki A., Korkolopoulou, Penelope, Piperi, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316974/ https://www.ncbi.nlm.nih.gov/pubmed/22530122 http://dx.doi.org/10.1155/2012/454957

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