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Ewing's Sarcoma: Development of RNA Interference-Based Therapy for Advanced Disease

Ewing's sarcoma tumors are associated with chromosomal translocation between the EWS gene and the ETS transcription factor gene. These unique target sequences provide opportunity for RNA interference(i)-based therapy. A summary of RNAi mechanism and therapeutically designed products including s...

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Detalles Bibliográficos
Autores principales: Simmons, Olivia, Maples, Phillip B., Senzer, Neil, Nemunaitis, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317005/
https://www.ncbi.nlm.nih.gov/pubmed/22523703
http://dx.doi.org/10.5402/2012/247657