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Superoxide Dismutase 3 Limits Collagen-Induced Arthritis in the Absence of Phagocyte Oxidative Burst
Extracellular superoxide dismutase (SOD3), an enzyme mediating dismutation of superoxide into hydrogen peroxide, has been shown to reduce inflammation by inhibiting macrophage migration into injured tissues. In inflamed tissues, superoxide is produced by the phagocytic NOX2 complex, which consists o...
Autores principales: | Kelkka, Tiina, Laurila, Juha Petteri, Sareila, Outi, Olofsson, Peter, Laukkanen, Mikko Olavi, Holmdahl, Rikard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317049/ https://www.ncbi.nlm.nih.gov/pubmed/22529530 http://dx.doi.org/10.1155/2012/730469 |
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