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Developing a Comparative Docking Protocol for the Prediction of Peptide Selectivity Profiles: Investigation of Potassium Channel Toxins

During the development of selective peptides against highly homologous targets, a reliable tool is sought that can predict information on both mechanisms of binding and relative affinities. These tools must first be tested on known profiles before application on novel therapeutic candidates. We therefo...

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Detalles Bibliográficos
Autores principales: Chen, Po-Chia, Kuyucak, Serdar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317111/
https://www.ncbi.nlm.nih.gov/pubmed/22474570
http://dx.doi.org/10.3390/toxins4020110