Re-oxygenation causes hypoxic tumor regression through restoration of p53 wild-type conformation and post-translational modifications

Hypoxic tumors are resistant to conventional therapies through indirect mechanisms such as the selection of resistant phenotype under chronic hypoxia. Hyperbaric oxygen (HBO) therapy has been shown to increase oxygen level and induce apoptosis in hypoxic tumor. However, it could produce significant...

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Detalles Bibliográficos
Autores principales: Gogna, R, Madan, E, Kuppusamy, P, Pati, U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317354/
https://www.ncbi.nlm.nih.gov/pubmed/22419115
http://dx.doi.org/10.1038/cddis.2012.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317354/
https://www.ncbi.nlm.nih.gov/pubmed/22419115
http://dx.doi.org/10.1038/cddis.2012.15

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