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Re-oxygenation causes hypoxic tumor regression through restoration of p53 wild-type conformation and post-translational modifications
Hypoxic tumors are resistant to conventional therapies through indirect mechanisms such as the selection of resistant phenotype under chronic hypoxia. Hyperbaric oxygen (HBO) therapy has been shown to increase oxygen level and induce apoptosis in hypoxic tumor. However, it could produce significant...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317354/ https://www.ncbi.nlm.nih.gov/pubmed/22419115 http://dx.doi.org/10.1038/cddis.2012.15 |