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Evidence for T Cell Help in the IgG Response against Tandemly Repetitive Trypanosoma cruzi B13 Protein in Chronic Chagas Disease Patients

The tandemly repetitive Trypanosoma cruzi B13 protein is an immunodominant antigen among Chagas disease patients. Such repetitive domains may behave as T-independent antigens. However, T cells can recognize B13 epitopes in an HLA class II-restricted fashion and could potentially provide cognate T ce...

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Detalles Bibliográficos
Autores principales:	Duranti, Marcia, Camargo, Ludmila, Victora, Gabriel, Ianni, Barbara, Buck, Paula, Mady, Charles, Kalil, Jorge, Zingales, Bianca, Cunha-Neto, Edecio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317355/ https://www.ncbi.nlm.nih.gov/pubmed/22523642 http://dx.doi.org/10.1155/2012/635873

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