Treatment with a Substance P Receptor Antagonist Is Neuroprotective in the Intrastriatal 6-Hydroxydopamine Model of Early Parkinson's Disease

Neuroinflammation and blood brain barrier (BBB) dysfunction have been implicated in the pathogenesis of Parkinson's disease (PD). The neuropeptide substance P (SP) is an important mediator of both neuroinflammation and BBB dysfunction through its NK1 receptor in a process known as neurogenic in...

Descripción completa

Detalles Bibliográficos
Autores principales: Thornton, Emma, Vink, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317489/
https://www.ncbi.nlm.nih.gov/pubmed/22485158
http://dx.doi.org/10.1371/journal.pone.0034138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317489/
https://www.ncbi.nlm.nih.gov/pubmed/22485158
http://dx.doi.org/10.1371/journal.pone.0034138

Ejemplares similares