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Gene Suppression of Mouse Testis In Vivo Using Small Interfering RNA Derived from Plasmid Vectors

We evaluated whether inhibiting gene expression by small interfering RNA (siRNA) can be used for an in vivo model using a germ cell-specific gene (Tex101) as a model target in mouse testis. We generated plasmid-based expression vectors of siRNA targeting the Tex101 gene and transfected them into pos...

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Detalles Bibliográficos
Autores principales: Takizawa, Takami, Ishikawa, Tomoko, Kosuge, Takuji, Mizuguchi, Yoshiaki, Sato, Yoko, Koji, Takehiko, Araki, Yoshihiko, Takizawa, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Society of Histochemistry and Cytochemistry 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317496/
https://www.ncbi.nlm.nih.gov/pubmed/22489107
http://dx.doi.org/10.1267/ahc.11024