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Critical Role of NADPH Oxidase in Neuronal Oxidative Damage and Microglia Activation following Traumatic Brain Injury
BACKGROUND: Oxidative stress is known to play an important role in the pathology of traumatic brain injury. Mitochondria are thought to be the major source of the damaging reactive oxygen species (ROS) following TBI. However, recent work has revealed that the membrane, via the enzyme NADPH oxidase c...
Autores principales: | Zhang, Quan-Guang, Laird, Melissa D., Han, Dong, Nguyen, Khoi, Scott, Erin, Dong, Yan, Dhandapani, Krishnan M., Brann, Darrell W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317633/ https://www.ncbi.nlm.nih.gov/pubmed/22485176 http://dx.doi.org/10.1371/journal.pone.0034504 |
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