Cargando…
Zfp296 Is a Novel, Pluripotent-Specific Reprogramming Factor
Expression of the four transcription factors Oct4, Sox2, Klf4, and c-Myc (OSKM) is sufficient to reprogram somatic cells into induced pluripotent stem (iPSCs). However, this process is slow and inefficient compared with the fusion of somatic cells with embryonic stem cells (ESCs), indicating that ES...
Autores principales: | Fischedick, Gerrit, Klein, Diana C., Wu, Guangming, Esch, Daniel, Höing, Susanne, Han, Dong Wook, Reinhardt, Peter, Hergarten, Kerstin, Tapia, Natalia, Schöler, Hans R., Sterneckert, Jared L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317644/ https://www.ncbi.nlm.nih.gov/pubmed/22485183 http://dx.doi.org/10.1371/journal.pone.0034645 |
Ejemplares similares
-
Counteracting Activities of OCT4 and KLF4 during Reprogramming to Pluripotency
por: Tiemann, Ulf, et al.
Publicado: (2014) -
Zfp296 knockout enhances chromatin accessibility and induces a unique state of pluripotency in embryonic stem cells
por: Miyazaki, Satsuki, et al.
Publicado: (2023) -
p53 connects tumorigenesis and reprogramming to pluripotency
por: Tapia, Natalia, et al.
Publicado: (2010) -
Reprogramming to Pluripotency through a Somatic Stem Cell Intermediate
por: Marthaler, Adele G., et al.
Publicado: (2013) -
Zfp322a Regulates Mouse ES Cell Pluripotency and Enhances Reprogramming Efficiency
por: Ma, Hui, et al.
Publicado: (2014)