Cargando…

Myosin Light-Chain Kinase Is Necessary for Membrane Homeostasis in Cochlear Inner Hair Cells

The structural homeostasis of the cochlear hair cell membrane is critical for all aspects of sensory transduction, but the regulation of its maintenance is not well understood. In this report, we analyzed the cochlear hair cells of mice with specific deletion of myosin light chain kinase (MLCK) in i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Guang-Jie, Wang, Fang, Chen, Chen, Xu, Lin, Zhang, Wen-Cheng, Fan, Chi, Peng, Ya-Jing, Chen, Jie, He, Wei-Qi, Guo, Shi-Ying, Zuo, Jian, Gao, Xia, Zhu, Min-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317649/ https://www.ncbi.nlm.nih.gov/pubmed/22485190 http://dx.doi.org/10.1371/journal.pone.0034894

Ejemplares similares

Myosin light chain kinase is a potential target for hypopharyngeal cancer treatment
por: Cao, Feng, et al.
Publicado: (2020)

Contributions of Myosin Light Chain Kinase to Regulation of Epithelial Paracellular Permeability and Mucosal Homeostasis
por: He, Wei-Qi, et al.
Publicado: (2020)

Myosin light chain kinase and myosin light chain phosphatase from Dictyostelium: effects of reversible phosphorylation on myosin structure and function
Publicado: (1987)

Transcriptomes of cochlear inner and outer hair cells from adult mice
por: Li, Yi, et al.
Publicado: (2018)

The Effect of Myosin Light Chain Kinase on the Occurrence and Development of Intracranial Aneurysm
por: Song, Yaying, et al.
Publicado: (2018)

Dynamic Regulation of Myosin Light Chain Phosphorylation by Rho-kinase
por: Kaneko-Kawano, Takako, et al.
Publicado: (2012)

Myosin Light Chain Kinase: A Potential Target for Treatment of Inflammatory Diseases
por: Xiong, Yongjian, et al.
Publicado: (2017)

Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I
por: Sevrieva, Ivanka R., et al.
Publicado: (2020)

Over-expression of myosin7A in cochlear hair cells of circling mice
por: Kim, Yoo Yeon, et al.
Publicado: (2017)

The Regulation of Intestinal Mucosal Barrier by Myosin Light Chain Kinase/Rho Kinases
por: Jin, Younggeon, et al.
Publicado: (2020)

Restoration of Cardiac Myosin Light Chain Kinase Ameliorates Systolic Dysfunction by Reducing Superrelaxed Myosin
por: Hitsumoto, Tatsuro, et al.
Publicado: (2023)

THE ULTRASTRUCTURE OF THE SENSORY HAIRS AND ASSOCIATED ORGANELLES OF THE COCHLEAR INNER HAIR CELL, WITH REFERENCE TO DIRECTIONAL SENSITIVITY
por: Duvall, Arndt J., et al.
Publicado: (1966)

Transcription Factors Expressed in Mouse Cochlear Inner and Outer Hair Cells
por: Li, Yi, et al.
Publicado: (2016)

Noise Exposure Potentiates Exocytosis From Cochlear Inner Hair Cells
por: Boero, Luis E., et al.
Publicado: (2021)

Myosin Light Chain Kinase Mediates Intestinal Barrier Disruption following Burn Injury
por: Chen, Chuanli, et al.
Publicado: (2012)

Myosin light chain kinase is necessary for post-shock mesenteric lymph drainage enhancement of vascular reactivity and calcium sensitivity in hemorrhagic-shocked rats
por: Zhang, Y.P., et al.
Publicado: (2013)

Molecular and cytological profiling of biological aging of mouse cochlear inner and outer hair cells
por: Liu, Huizhan, et al.
Publicado: (2022)

Association of myosin light chain kinase with lymphocyte membrane- cytoskeleton complex
Publicado: (1982)

Ardipusilloside-I stimulates gastrointestinal motility and phosphorylation of smooth muscle myosin by myosin light chain kinase
por: Xu, Zhili, et al.
Publicado: (2017)

Nonmuscle Myosin Heavy Chain ⅡA-Mediated Exosome Release via Regulation of the Rho-Associated Kinase 1/Myosin Light Chains/Actin Pathway
por: Lv, Yanni, et al.
Publicado: (2020)

Expression of Calmodulin and Myosin Light Chain Kinase during Larval Settlement of the Barnacle Balanus amphitrite
por: Chen, Zhang-Fan, et al.
Publicado: (2012)

Circular RNA Myosin Light Chain Kinase (MYLK) Promotes Prostate Cancer Progression through Modulating Mir-29a Expression
por: Dai, Yuanqing, et al.
Publicado: (2018)

Inner Hair Cell Loss Disrupts Hearing and Cochlear Function Leading to Sensory Deprivation and Enhanced Central Auditory Gain
por: Salvi, Richard, et al.
Publicado: (2017)

Diffusion of myosin light chain kinase on actin: A mechanism to enhance myosin phosphorylation rates in smooth muscle
por: Hong, Feng, et al.
Publicado: (2015)

Myosin light chain kinase-driven myosin II turnover regulates actin cortex contractility during mitosis
por: Taneja, Nilay, et al.
Publicado: (2021)

MicroRNA-126 Modulates Palmitate-Induced Migration in HUVECs by Downregulating Myosin Light Chain Kinase via the ERK/MAPK Pathway
por: Wang, Yi, et al.
Publicado: (2020)

Effects of phosphorylation by myosin light chain kinase on the structure of Limulus thick filaments
Publicado: (1991)

Localization and Activity of Myosin Light Chain Kinase Isoforms during the Cell Cycle
por: Poperechnaya, Angela, et al.
Publicado: (2000)

The Effects of Neuregulin on Cardiac Myosin Light Chain Kinase Gene-Ablated Hearts
por: Chang, Audrey N., et al.
Publicado: (2013)

Heart Failure Induced by Perinatal Ablation of Cardiac Myosin Light Chain Kinase
por: Islam, Yasmin F. K., et al.
Publicado: (2016)

Myosin Light Chain Kinase Modulates to Improve Myocardial Hypoxia/Reoxygenation Injury
por: Zhang, Qibo, et al.
Publicado: (2022)

Myosin light chain kinase regulates cell polarization independently of membrane tension or Rho kinase
por: Lou, Sunny S., et al.
Publicado: (2015)

Slit and Netrin-1 guide cranial motor axon pathfinding via Rho-kinase, myosin light chain kinase and myosin II
por: Murray, Ailish, et al.
Publicado: (2010)

High glucose upregulates myosin light chain kinase to induce microfilament cytoskeleton rearrangement in hippocampal neurons
por: Zhu, Liying, et al.
Publicado: (2018)

Cochlear gene therapy with ancestral AAV in adult mice: complete transduction of inner hair cells without cochlear dysfunction
por: Suzuki, Jun, et al.
Publicado: (2017)

Position-dependent patterning of spontaneous action potentials in immature cochlear inner hair cells
por: Johnson, Stuart L., et al.
Publicado: (2011)

Inner Ear Hair Cell Protection in Mammals against the Noise-Induced Cochlear Damage
por: Waqas, Muhammad, et al.
Publicado: (2018)

Individual synaptic vesicles mediate stimulated exocytosis from cochlear inner hair cells
por: Grabner, Chad Paul, et al.
Publicado: (2018)

Localized disorganization of the cochlear inner hair cell synaptic region after noise exposure
por: Bullen, Anwen, et al.
Publicado: (2018)

Sensory transduction is required for normal development and maturation of cochlear inner hair cell synapses
por: Lee, John, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dsmb28ip16df9l0pvu0c9fanpp