Cargando…

Primary Study for the Therapeutic Dose and Time Window of Picroside II in Treating Cerebral Ischemic Injury in Rats

The aim of this study was to explore the optimal therapeutic dose and time window of picroside II for treating cerebral ischemic injury in rats according to the orthogonal test. The middle cerebral artery occlusion (MCAO) models were established by intraluminally inserting a thread into middle cereb...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pei, Haitao, Su, Xi, Zhao, Li, Li, Hongyun, Guo, Yunliang, Zhang, Menizeng, Xin, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317673/ https://www.ncbi.nlm.nih.gov/pubmed/22489110 http://dx.doi.org/10.3390/ijms13032551

Ejemplares similares

Optimal therapeutic dose and time window of picroside II in cerebral ischemic injury
por: Liu, Guangyi, et al.
Publicado: (2014)

Picroside II Inhibits Neuronal Apoptosis and Improves the Morphology and Structure of Brain Tissue following Cerebral Ischemic Injury in Rats
por: Wang, Tingting, et al.
Publicado: (2015)

Anti-inflammation effects of picroside 2 in cerebral ischemic injury rats
por: Guo, Yunliang, et al.
Publicado: (2010)

The neuroprotective effect of picroside II via regulating the expression of myelin basic protein after cerebral ischemia injury in rats
por: Zhao, Li, et al.
Publicado: (2014)

Picroside II protects the blood-brain barrier by inhibiting the oxidative signaling pathway in cerebral ischemia-reperfusion injury
por: Zhai, Li, et al.
Publicado: (2017)

Picroside I and Picroside II from Tissue Cultures of Picrorhiza kurroa
por: Ganeshkumar, Yamjala, et al.
Publicado: (2017)

Neuroprotective Properties of Picroside II in a Rat Model of Focal Cerebral Ischemia
por: Li, Qin, et al.
Publicado: (2010)

Protective effect of picroside II on myocardial ischemia reperfusion injury in rats
por: Wu, Nan, et al.
Publicado: (2014)

Effect of picroside II on hind limb ischemia reperfusion injury in rats
por: Kılıç, Yiğit, et al.
Publicado: (2017)

Effect of picroside II on apoptosis induced by renal ischemia/reperfusion injury in rats
por: WANG, LEI, et al.
Publicado: (2015)

Neutrophilic Lung Inflammation Suppressed by Picroside II Is Associated with TGF-β Signaling
por: Noh, Soohwan, et al.
Publicado: (2015)

Picroside II protects myocardium from ischemia/reperfusion-induced injury through inhibition of the inflammatory response
por: Li, Jian-Zhe, et al.
Publicado: (2016)

Effect of picroside II on erythrocyte deformability and lipid peroxidation in rats subjected to hind limb ischemia reperfusion injury
por: Çomu, Faruk Metin, et al.
Publicado: (2016)

Intervention by picroside II on FFAs induced lipid accumulation and lipotoxicity in HepG2 cells
por: Dhami-Shah, Hiteshi, et al.
Publicado: (2021)

Picroside II Shows Protective Functions for Severe Acute Pancreatitis in Rats by Preventing NF-κB-Dependent Autophagy
por: Piao, Xuehua, et al.
Publicado: (2017)

Picroside II attenuates hyperhomocysteinemia‐induced endothelial injury by reducing inflammation, oxidative stress and cell apoptosis
por: Wang, Yunkai, et al.
Publicado: (2018)

Picroside II attenuates ischemia/reperfusion testicular injury by alleviating oxidative stress and apoptosis through reducing nitric oxide synthesis
por: Li, Yanze, et al.
Publicado: (2019)

Picroside II Improves Severe Acute Pancreatitis-Induced Hepatocellular Injury in Rats by Affecting JAK2/STAT3 Phosphorylation Signaling
por: Piao, Xuehua, et al.
Publicado: (2021)

Picroside II protects rat kidney against ischemia/reperfusion-induced oxidative stress and inflammation by the TLR4/NF-κB pathway
por: WANG, LEI, et al.
Publicado: (2015)

Picroside II attenuates fatty acid accumulation in HepG2 cells via modulation of fatty acid uptake and synthesis
por: Dhami-Shah, Hiteshi, et al.
Publicado: (2018)

NGS Transcriptomes and Enzyme Inhibitors Unravel Complexity of Picrosides Biosynthesis in Picrorhiza kurroa Royle ex. Benth
por: Shitiz, Kirti, et al.
Publicado: (2015)

Picroside II Attenuates Airway Inflammation by Downregulating the Transcription Factor GATA3 and Th2-Related Cytokines in a Mouse Model of HDM-Induced Allergic Asthma
por: Choi, Jin, et al.
Publicado: (2016)

Astragalus injection protects cerebral ischemic injury by inhibiting neuronal apoptosis and the expression of JNK3 after cerebral ischemia reperfusion in rats
por: Liu, Guangyi, et al.
Publicado: (2013)

Development and Validation of RP-HPLC Method for Simultaneous Estimation of Picroside I, Plumbagin, and Z-guggulsterone in Tablet Formulation
por: Akhade, Meenakshi S., et al.
Publicado: (2013)

Therapeutic Window for Cycloheximide Treatment after Hypoxic-Ischemic Brain Injury in Neonatal Rats
por: Park, Won Soon, et al.
Publicado: (2006)

Modular Design of Picroside-II Biosynthesis Deciphered through NGS Transcriptomes and Metabolic Intermediates Analysis in Naturally Variant Chemotypes of a Medicinal Herb, Picrorhiza kurroa
por: Kumar, Varun, et al.
Publicado: (2017)

Correction: Picroside II Attenuates Airway Inflammation by Downregulating the Transcription Factor GATA3 and Th2-Related Cytokines in a Mouse Model of HDM-Induced Allergic Asthma
por: Choi, Jin, et al.
Publicado: (2017)

Synergistic Neuroprotection by a PAF Antagonist Plus a Docosanoid in Experimental Ischemic Stroke: Dose-Response and Therapeutic Window
por: Reid, Madigan M., et al.
Publicado: (2022)

Picroside II Isolated from Pseudolysimachion rotundum var. subintegrum Inhibits Glucocorticoid Refractory Serum Amyloid A (SAA) Expression and SAA-induced IL-33 Secretion
por: Lee, Kiram, et al.
Publicado: (2019)

Protective effect of tanshinone IIA on the brain and its therapeutic time window in rat models of cerebral ischemia-reperfusion
por: TANG, QIQIANG, et al.
Publicado: (2014)

Bone Morphogenetic Protein-7 Ameliorates Cerebral Ischemia and Reperfusion Injury via Inhibiting Oxidative Stress and Neuronal Apoptosis
por: Pei, Haitao, et al.
Publicado: (2013)

Exogenous feeding of immediate precursors reveals synergistic effect on picroside-I biosynthesis in shoot cultures of Picrorhiza kurroa Royle ex Benth
por: Kumar, Varun, et al.
Publicado: (2016)

Picroside II Improves Severe Acute Pancreatitis-Induced Intestinal Barrier Injury by Inactivating Oxidative and Inflammatory TLR4-Dependent PI3K/AKT/NF-κB Signaling and Improving Gut Microbiota
por: Piao, Xuehua, et al.
Publicado: (2020)

Clinical Evaluation of Herbal Medicine (ICH-012) in Treating Acute Cerebral Haemorrhage: Safety and Efficacy from 6- to 72-Hour Time Window (CRRICHTrial-II)
por: Zhang, Qixin, et al.
Publicado: (2018)

Nanoparticles augment the therapeutic window of RT and immunotherapy for treating cancers: pivotal role of autophagy
por: Wu, Yuan-Hua, et al.
Publicado: (2023)

Combination therapy for ischemic stroke: Novel approaches to lengthen therapeutic window of tissue plasminogen activator
por: Knecht, Talia, et al.
Publicado: (2018)

“Time lost is clot resolution lost”: the neglected perspective of the therapeutic time window for ischemic stroke
por: De Michele, Manuela, et al.
Publicado: (2023)

Cocktail treatment, a promising strategy to treat acute cerebral ischemic stroke?
por: Liang, Li-jun, et al.
Publicado: (2016)

Bone Fracture Pre-Ischemic Stroke Exacerbates Ischemic Cerebral Injury in Mice
por: Wang, Liang, et al.
Publicado: (2016)

Evolution of the Thrombolytic Treatment Window for Acute Ischemic Stroke
por: Stemer, Andrew, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_n8onmlik03878ci5fd2o9875er