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Astragalin from Cassia alata Induces DNA Adducts in Vitro and Repairable DNA Damage in the Yeast Saccharomyces cerevisiae

Reverse phase-solid phase extraction from Cassia alata leaves (CaRP) was used to obtain a refined extract. Higher than wild-type sensitivity to CaRP was exhibited by 16 haploid Saccharomyces cerevisiae mutants with defects in DNA repair and membrane transport. CaRP had a strong DPPH free radical sca...

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Detalles Bibliográficos
Autores principales: Saito, Samuel, Silva, Givaldo, Santos, Regineide Xavier, Gosmann, Grace, Pungartnik, Cristina, Brendel, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317691/
https://www.ncbi.nlm.nih.gov/pubmed/22489129
http://dx.doi.org/10.3390/ijms13032846