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An extended γ-tubulin ring functions as a stable platform in microtubule nucleation

γ-Tubulin complexes are essential for microtubule (MT) nucleation. The γ-tubulin small complex (γ-TuSC) consists of two molecules of γ-tubulin and one molecule each of Spc97 and Spc98. In vitro, γ-TuSCs oligomerize into spirals of 13 γ-tubulin molecules per turn. However, the properties and numbers...

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Detalles Bibliográficos
Autores principales:	Erlemann, Sarah, Neuner, Annett, Gombos, Linda, Gibeaux, Romain, Antony, Claude, Schiebel, Elmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317808/ https://www.ncbi.nlm.nih.gov/pubmed/22472440 http://dx.doi.org/10.1083/jcb.201111123

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