Cargando…

Measurement of the plasma levels of antibodies against the polymorphic vaccine candidate apical membrane antigen 1 in a malaria-exposed population

BACKGROUND: Establishing antibody correlates of protection against malaria in human field studies and clinical trials requires, amongst others, an accurate estimation of antibody levels. For polymorphic antigens such as apical membrane antigen 1 (AMA1), this may be confounded by the occurrence of a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kusi, Kwadwo A, Dodoo, Daniel, Bosomprah, Samuel, van der Eijk, Marjolein, Faber, Bart W, Kocken, Clemens HM, Remarque, Edmond J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317819/ https://www.ncbi.nlm.nih.gov/pubmed/22299616 http://dx.doi.org/10.1186/1471-2334-12-32

Ejemplares similares

Immunization with different PfAMA1 alleles in sequence induces clonal imprint humoral responses that are similar to responses induced by the same alleles as a vaccine cocktail in rabbits
por: Kusi, Kwadwo A, et al.
Publicado: (2011)

Safety and immunogenicity of multi-antigen AMA1-based vaccines formulated with CoVaccine HT™ and Montanide ISA 51 in rhesus macaques
por: Kusi, Kwadwo A, et al.
Publicado: (2011)

Low Levels of Polymorphisms and No Evidence for Diversifying Selection on the Plasmodium knowlesi Apical Membrane Antigen 1 Gene
por: Faber, Bart W., et al.
Publicado: (2015)

Generation of Humoral Immune Responses to Multi-Allele PfAMA1 Vaccines; Effect of Adjuvant and Number of Component Alleles on the Breadth of Response
por: Kusi, Kwadwo A., et al.
Publicado: (2010)

Identification of adjuvants for clinical trials performed with Plasmodium falciparum AMA1 in rabbits
por: Younis, Sumera, et al.
Publicado: (2019)

Variations in the quality of malaria-specific antibodies with transmission intensity in a seasonal malaria transmission area of Northern Ghana
por: Kusi, Kwadwo A., et al.
Publicado: (2017)

Interplay between AMA1 immunisation and parasite challenge leads to protection against malaria infection in rhesus macaques
por: Hamid, Muzamil Mahdi Abdel, et al.
Publicado: (2010)

Humoral Immune Response to Mixed PfAMA1 Alleles; Multivalent PfAMA1 Vaccines Induce Broad Specificity
por: Kusi, Kwadwo A., et al.
Publicado: (2009)

Crystal Structure of Plasmodium knowlesi Apical Membrane Antigen 1 and Its Complex with an Invasion-Inhibitory Monoclonal Antibody
por: Vulliez-Le Normand, Brigitte, et al.
Publicado: (2015)

Production, Quality Control, Stability and Pharmacotoxicity of a Malaria Vaccine Comprising Three Highly Similar PfAMA1 Protein Molecules to Overcome Antigenic Variation
por: Faber, Bart W., et al.
Publicado: (2016)

Seroprevalence of Antibodies against Plasmodium falciparum Sporozoite Antigens as Predictive Disease Transmission Markers in an Area of Ghana with Seasonal Malaria Transmission
por: Kusi, Kwadwo A., et al.
Publicado: (2016)

Malaria infection by sporozoite challenge induces high functional antibody titres against blood stage antigens after a DNA prime, poxvirus boost vaccination strategy in Rhesus macaques
por: Mahdi Abdel Hamid, Muzamil, et al.
Publicado: (2011)

Cohort study of the association of antibody levels to AMA1, MSP1(19), MSP3 and GLURP with protection from clinical malaria in Ghanaian children
por: Dodoo, Daniel, et al.
Publicado: (2008)

Antibody levels to multiple malaria vaccine candidate antigens in relation to clinical malaria episodes in children in the Kasena-Nankana district of Northern Ghana
por: Dodoo, Daniel, et al.
Publicado: (2011)

Accelerated phase Ia/b evaluation of the malaria vaccine candidate PfAMA1 DiCo demonstrates broadening of humoral immune responses
por: Remarque, Edmond J., et al.
Publicado: (2021)

Anti-sporozoite antibodies as alternative markers for malaria transmission intensity estimation
por: Kusi, Kwadwo A, et al.
Publicado: (2014)

Humoral Immune Responses to a Single Allele PfAMA1 Vaccine in Healthy Malaria-Naïve Adults
por: Remarque, Edmond J., et al.
Publicado: (2012)

The Quantity and Quality of African Children's IgG Responses to Merozoite Surface Antigens Reflect Protection against Plasmodium falciparum Malaria
por: Courtin, David, et al.
Publicado: (2009)

Designing malaria vaccines to circumvent antigen variability()
por: Ouattara, Amed, et al.
Publicado: (2015)

Overcoming Antigenic Diversity by Enhancing the Immunogenicity of Conserved Epitopes on the Malaria Vaccine Candidate Apical Membrane Antigen-1
por: Dutta, Sheetij, et al.
Publicado: (2013)

Correction: Overcoming Antigenic Diversity by Enhancing the Immunogenicity of Conserved Epitopes on the Malaria Vaccine Candidate Apical Membrane Antigen-1
por: Dutta, Sheetij, et al.
Publicado: (2014)

Vaccination with Plasmodium knowlesi AMA1 Formulated in the Novel Adjuvant Co-Vaccine HT™ Protects against Blood-Stage Challenge in Rhesus Macaques
por: Mahdi Abdel Hamid, Muzamil, et al.
Publicado: (2011)

Sterile protection against relapsing malaria with a single-shot vaccine
por: Pasini, Erica M., et al.
Publicado: (2022)

Measuring naturally acquired immune responses to candidate malaria vaccine antigens in Ghanaian adults
por: Dodoo, Daniel, et al.
Publicado: (2011)

Evaluation of Chimpanzee Adenovirus and MVA Expressing TRAP and CSP from Plasmodium cynomolgi to Prevent Malaria Relapse in Nonhuman Primates
por: Kim, Young Chan, et al.
Publicado: (2020)

Sample size calculation for multicentre efficacy trials of blood-stage malaria antigens
por: Bosomprah, Samuel
Publicado: (2013)

A mathematical model of seropositivity to malaria antigen, allowing seropositivity to be prolonged by exposure
por: Bosomprah, Samuel
Publicado: (2014)

Identification of Plasmodium falciparum circumsporozoite protein-specific CD8+ T cell epitopes in a malaria exposed population
por: Kusi, Kwadwo A., et al.
Publicado: (2020)

Phase 1 randomized controlled trial to evaluate the safety and immunogenicity of recombinant Pichia pastoris-expressed Plasmodium falciparum apical membrane antigen 1 (PfAMA1-FVO [25-545]) in healthy Malian adults in Bandiagara
por: Thera, Mahamadou A., et al.
Publicado: (2016)

A novel live-dead staining methodology to study malaria parasite viability
por: Pasini, Erica M, et al.
Publicado: (2013)

Novel Strategies for Malaria Vaccine Design
por: Frimpong, Augustina, et al.
Publicado: (2018)

Reduced CD36-dependent tissue sequestration of Plasmodium-infected erythrocytes is detrimental to malaria parasite growth in vivo
por: Fonager, Jannik, et al.
Publicado: (2012)

Antibodies to Polymorphic Invasion-Inhibitory and Non-Inhibitory Epitopes of Plasmodium falciparum Apical Membrane Antigen 1 in Human Malaria
por: Mugyenyi, Cleopatra K., et al.
Publicado: (2013)

Global Population Structure of the Genes Encoding the Malaria Vaccine Candidate, Plasmodium vivax Apical Membrane Antigen 1 (PvAMA1)
por: Arnott, Alicia, et al.
Publicado: (2013)

The prevalence of submicroscopic Plasmodium falciparum gametocyte carriage and multiplicity of infection in children, pregnant women and adults in a low malaria transmission area in Southern Ghana
por: Lamptey, Helena, et al.
Publicado: (2018)

A STAT6 Intronic Single-Nucleotide Polymorphism is Associated with Clinical Malaria in Ghanaian Children
por: Amoako-Sakyi, Daniel, et al.
Publicado: (2016)

A Malaria Vaccine Based on the Polymorphic Block 2 Region of MSP-1 that Elicits a Broad Serotype-Spanning Immune Response
por: Cowan, Graeme J. M., et al.
Publicado: (2011)

Patterns of inflammatory responses and parasite tolerance vary with malaria transmission intensity
por: Ademolue, Temitope W., et al.
Publicado: (2017)

Activity of Herbal Medicines on Plasmodium falciparum Gametocytes: Implications for Malaria Transmission in Ghana
por: Amoah, Linda Eva, et al.
Publicado: (2015)

Antigenicity and immune correlate assessment of seven Plasmodium falciparum antigens in a longitudinal infant cohort from northern Ghana
por: Kusi, Kwadwo Asamoah, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7uof2k89ab7emfk5t5b3jmq2gs