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Acetate supplementation modulates brain histone acetylation and decreases interleukin-1β expression in a rat model of neuroinflammation
BACKGROUND: Long-term acetate supplementation reduces neuroglial activation and cholinergic cell loss in a rat model of lipopolysaccharide-induced neuroinflammation. Additionally, a single dose of glyceryl triacetate, used to induce acetate supplementation, increases histone H3 and H4 acetylation an...
Autores principales: | Soliman, Mahmoud L, Smith, Mark D, Houdek, Heidi M, Rosenberger, Thad A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317831/ https://www.ncbi.nlm.nih.gov/pubmed/22413888 http://dx.doi.org/10.1186/1742-2094-9-51 |
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